Skiepai nuo vėjaraupių

As taip pat netaupau vaiko sveikatos saskaita,bet mano nuomone yra geriau neskiepyti.

Ko gero ir gydytoja, ir žurnalas buvo neteisūs 2007 m kovo mėnesio New england journal of medicine paskelbto tyrimo rezultatai teigia, kad praėjus 5 metams po vakcinavimo vėjaraupių vakcina, vakcinuotų vaikų grupėje ženkliai išauga susirgimų skaičius. Maždaug 15 proc. vakcinuotų vaikų nesusiformuoja apsaugai reikalingas antikūnų lygmuo. Imuninės apsaugos palaikymui siūloma revakcinacija, tačiau pridedama, jog "No long-term data are available on the duration of immunity afforded by the second dose of vaccine. "

o lietuviškai šitos eilutės nebuvo galima parašyti?

Galima, tiesiog patingėjau versti ir nukopijavau tiesiai iš straipsnio " Nėra ilgalaikių tyrimų duomenų apie imuniteto trukmę po antros vakcinos dozės"

nu gerai, paimkim visa tyrima is New england journal of medicine

The Effectiveness of the Varicella Vaccine in Clinical Practice

Background A live attenuated varicella vaccine was approved for use in the United States in March 1995 and is recommended for all susceptible persons 12 months of age or older.

Methods To assess the effectiveness of the varicella vaccine, we conducted a case–control study with two controls per child with chickenpox, matched according to both age and pediatric practice. Children with potential cases of chickenpox were identified by active surveillance of pediatric practices in the New Haven, Connecticut, area. Research assistants visited the children on day 3, 4, or 5 of the illness, assessed the severity of the illness, and collected samples from lesions to test for varicella–zoster virus by the polymerase chain reaction (PCR).

Results From March 1997 through November 2000, data collection was completed for 330 potential cases, of which 243 (74 percent) were in children who had positive PCR tests for varicella–zoster virus. Of the 56 vaccinated children with chickenpox, 86 percent had mild disease, whereas only 48 percent of the 187 unvaccinated children with chickenpox had mild disease (P<0.001 ). Among the 202 children with PCR-confirmed varicella–zoster virus and their 389 matched controls, 23 percent of the children with chickenpox and 61 percent of the matched controls had received the vaccine (vaccine effectiveness, 85 percent; 95 percent confidence interval, 78 to 90 percent; P<0.001). Against moderately severe and severe disease the vaccine was 97 percent effective (95 percent confidence interval, 93 to 99 percent). The effectiveness of the vaccine was virtually unchanged (87 percent) after adjustment for potential confounders by means of conditional logistic regression.

Conclusions Varicella vaccine is highly effective as used in clinical practice.



bet kaip gerai istraukti kad NET 15 PROC. IMUNITETAS NESUSIFORMUOJA.
Man atrodo 85 proc efektyvumo gan neblogas rezultatas, tuo labiau kad pries sunkias formas duoda net 97 proc. efektyvumo

o del imuniteto isliekimo jau kalbejom, jeigu virusas cirkuliuos laisvai , revakcinacijos nereikalingos.
Longer-term follow-up studies in vaccinated persons have been reported.9,10 The protective concentrations of antibody among vaccinated persons in Japan have persisted for more than 20 years after immunization,11 but this persistence may be due in part to a booster effect from exposure to persons with chickenpox in a country where the vaccine is not used widely12 and where the incidence of chickenpox remains high.

taigy logiskai mastant dabar, kai vakicnacija dar nera visuotine, paskiepyjus vaika, jis gaus ilgesni imuniteta, negu veliau kai skipas bus itrauktas i privalomu skiepu kalendoriu

kai vaikas mažas - tada taip, geriau neskiepyti, bet jei iki 10 metų nepersirgo - tada.... tiesio būtina, taip apsisaugant bent jau nuo komplikacijų.. negi nesusidūrėt su atvejais, kai paaugliai suserga vėjaraupiais??? baisios komplikacijos - astma ir pan..

Rituska, aš neginčyju vakcinos efektyvumo Tiesiog bandau pasakyti, kad 20 apsaugos metų apie kuriuos kalbama tėveliams, ketinantiems skiepyti savo atžalas yra labiau teorinis, nei praktinis skaičius. Beje, skaitėme ne tą patį straipsnį
Loss of Vaccine-Induced Immunity to Varicella over Time
Background
The introduction of universal varicella vaccination in 1995 has substantially reduced
varicella-related morbidity and mortality in the United States. However, it remains
unclear whether vaccine-induced immunity wanes over time, a condition that may
result in increased susceptibility later in life, when the risk of serious complications
may be greater than in childhood.
Results
A total of 11,356 subjects were reported to have varicella during the surveillance
period, of whom 1080 (9.5%) had breakthrough disease. Children between the ages
of 8 and 12 years who had been vaccinated at least 5 years previously were significantly
more likely to have moderate or severe disease than were those who had been
vaccinated less than 5 years previously (risk ratio, 2.6; 95% confidence interval [CI],
1.2 to 5.8). The annual rate of breakthrough varicella significantly increased with
the time since vaccination, from 1.6 cases per 1000 person-years (95% CI, 1.2 to 2.0)
within 1 year after vaccination to 9.0 per 1000 person-years (95% CI, 6.9 to 11.7) at
5 years and 58.2 per 1000 person-years (95% CI, 36.0 to 94.0) at 9 years.
Conclusions
A second dose of varicella vaccine, now recommended for all children, could improve
protection from both primary vaccine failure and waning vaccine-induced immunity.
reserved.
Downloaded from www.nejm.org on April 24, 2007 . Copyright © 2007 Massachusetts Medical Society. All rights
Dėl vieno dalyko tau pritarčiau:kol pas mus dauguma neskiepytų ir didelė tikimybė susidurti su "laukiniu" virusu, galima tikėtis, kad dėl vadinamo "booster" efekto vakcinos apsauga truks ilgiau.

aha, aciu uz straipsniali ...is tikruju tai as sitos temos pradzioje ir kalbejau, kad nu netikiu as kad vienas skiepas visam gyvenimui todel dar ir nepaskiepyjau. taciau ir nelabai noriu kad vaikas sirgtu vejaraupiais, nes to viruso virulentiskumas yra didesnis ir imunitetas ir islieka ilgiau butent todel kas virusas lieka orgaznizme ir nusilpus lastelinio imuniteto pajegumui (fiziologinemis aplinkybemis – pagyvenusiems zmonems), pasireiskia antraja savo klinikine forma – juostine pusleline (herpes zoster).

Visiskai susimaisiau ,jau dabar pradejau abejoti ar man skiepyti vaika nuo vejaraupiu ar ne !!! aisku suprantu ,kad skiepas nesenai israstas ir praktiskai neirodyta kiek jis ten metu apsaugo...bet ir ligos bijau ! juk buna ir sunkiu komplikaciju ,nesu naivi ,kad vaikuj susirgus viens du ir vaikas pasveiks ! KA MAN DARYTI !
Papildyta:



NA IR KAIP ? KAS PATARE SKIEPYTIS ?

Skaičiau tavo pamąstymus dėl revakcinacijos, todėl ir pati "užsikabinau" ir pradėjau ieškoti informacijos ta tema Įdomu, kaip ten su tuo herpes zooster praktikoje: ar yra atliktų klinikinių tyrimų, įrodančių patikimą apsaugą nuo šios vėjaraupių viruso klinikinės formos

vakar buvom endemike,skiepijomes pakartotinai nuo erkinio encifalito ir paklausiau del vejerupiu,nes pediatre patare skiepyt,ten pasake jei turit pinigu aisku skiepikit...pasake kad imunitetas visam gyvenimui,o as sakau jog girdejau kad 20 metu,bet man tiksliai nieko neatsake,tai dabar irgi nezinau ka daryti....

o ką endemike tau patarė?